.Attributes Medicine, Released online: 18 September 2024 doi:10.1038/ s41591-024-03300-3Genomic and also epidemiologic analyses uncovered that a novel reassortant viral descent of the Oropouche virus, which has actually been spreading in the western Amazon region of Brazil for regarding a many years, is connected with the recent human episodes in between 2022 as well as 2024.